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Author: [Your Name/Institution] Date: April 2026 Journal: Journal of Cardiovascular Imaging & Diagnostics (hypothetical) Abstract The aortic root diameter varies significantly with age, body size, and sex. A Z-score—defined as the number of standard deviations a measured value deviates from the population mean—standardizes this variation, enabling precise assessment of aortic root size. This paper reviews the mathematical derivation of Z-scores, the necessary anthropometric parameters (body surface area, height, age), and the critical role of Z-scores in diagnosing aortic root aneurysms, predicting dissection risk in connective tissue disorders (e.g., Marfan syndrome), and guiding surgical intervention. Limitations, including population-specific nomograms and measurement variability, are also discussed.