In the lexicon of electrocardiography (ECG) and clinical cardiology, few phrases carry as much weight—and as much potential for ambiguity—as the interpretive statement: “Cannot rule out inferior infarct.” This is not a definitive diagnosis, nor is it a dismissal of pathology. Instead, it resides in a gray zone of high clinical vigilance, where pattern recognition meets anatomical reality, and where the cost of missing a true event is measured in myocardial function and survival.
The wise clinician reads this phrase and does not ask, “Is it or isn’t it?” but rather, “What else could it be, and how quickly can I get troponin and an echo?” In that uncertainty lies the art of medicine: balancing the harm of missing a treatable infarct against the harm of unnecessary catheterization, all while the ECG machine’s cautious algorithm reminds us that some truths are not written in voltage, but in time. cannot rule out inferior infarct